The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module

Streptococcus pyogenes is an exclusively human pathogen. Streptococcal attachment to and entry into epithelial cells is a prerequisite for a successful infection of the human host and requires adhesins. Here, we demonstrate that the multidomain protein Epf from S. pyogenes serotype M49 is a streptoc...

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Hlavní autoři: Linke, Christian, Siemens, Nikolai, Oehmcke, Sonja, Radjainia, Mazdak, Law, Ruby H. P., Whisstock, James C., Baker, Edward N., Kreikemeyer, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488087/
https://ncbi.nlm.nih.gov/pubmed/22977243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.376434
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