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Isozyme-specific Interaction of Protein Kinase Cδ with Mitochondria Dissected Using Live Cell Fluorescence Imaging

PKCδ signaling to mitochondria has been implicated in both mitochondrial apoptosis and metabolism. However, the mechanism by which PKCδ interacts with mitochondria is not well understood. Using FRET-based imaging, we show that PKCδ interacts with mitochondria by a novel and isozyme-specific mechanis...

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Bibliografiske detaljer
Main Authors: Wu-Zhang, Alyssa X., Murphy, Anne N., Bachman, Mackenzie, Newton, Alexandra C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488061/
https://ncbi.nlm.nih.gov/pubmed/22988234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412635
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