Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.
Taxol, a potent promoter of microtubule polymerization in vitro, induces massive assembly of free microtubules in cultured cells as visualized by immunocytochemistry and electron microscopy. The centrosomes and kinetochores largely lost their capacity to organize microtubule assembly, as became evid...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1981
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5608 |
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