Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores.

Taxol, a potent promoter of microtubule polymerization in vitro, induces massive assembly of free microtubules in cultured cells as visualized by immunocytochemistry and electron microscopy. The centrosomes and kinetochores largely lost their capacity to organize microtubule assembly, as became evid...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	De Brabander, M, Geuens, G, Nuydens, R, Willebrords, R, De Mey, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6117858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.9.5608
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