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Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics
Microtubule dynamics are crucial for mitotic spindle assembly and chromosome movement. Suppression of dynamics by Taxol appears responsible for the drug's potent ability to inhibit mitosis and cell proliferation. Although Taxol is an important chemotherapeutic agent, development of resistance l...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The National Academy of Sciences
2001
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58799/ https://ncbi.nlm.nih.gov/pubmed/11562465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191388598 |
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