High-throughput comparison of gene fitness among related bacteria

BACKGROUND: The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal diffe...

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Main Authors: Canals, Rocio, Xia, Xiao-Qin, Fronick, Catrina, Clifton, Sandra W, Ahmer, Brian MM, Andrews-Polymenis, Helene L, Porwollik, Steffen, McClelland, Michael
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487940/
https://ncbi.nlm.nih.gov/pubmed/22646920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-212
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