High-throughput comparison of gene fitness among related bacteria

BACKGROUND: The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal diffe...

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Hlavní autoři: Canals, Rocio, Xia, Xiao-Qin, Fronick, Catrina, Clifton, Sandra W, Ahmer, Brian MM, Andrews-Polymenis, Helene L, Porwollik, Steffen, McClelland, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487940/
https://ncbi.nlm.nih.gov/pubmed/22646920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-212
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