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High-throughput comparison of gene fitness among related bacteria

BACKGROUND: The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal diffe...

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Detalhes bibliográficos
Main Authors: Canals, Rocio, Xia, Xiao-Qin, Fronick, Catrina, Clifton, Sandra W, Ahmer, Brian MM, Andrews-Polymenis, Helene L, Porwollik, Steffen, McClelland, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487940/
https://ncbi.nlm.nih.gov/pubmed/22646920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-212
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