Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis

BACKGROUND: Interactions between Th1 and Th2 immune responses are of importance to the onset and development of allergic disorders. A Toll-like receptor 7 agonist such as AZD8848 may have potential as a treatment for allergic airway disease by skewing the immune system away from a Th2 profile. OBJEC...

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Main Authors: Greiff, Lennart, Cervin, Anders, Ahlström-Emanuelsson, Cecilia, Almqvist, Gun, Andersson, Morgan, Dolata, Jan, Eriksson, Leif, Högestätt, Edward, Källén, Anders, Norlén, Per, Sjölin, Inga-Lisa, Widegren, Henrik
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487914/
https://ncbi.nlm.nih.gov/pubmed/22726593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-53
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