Effects of a dual CCR3 and H(1)-antagonist on symptoms and eosinophilic inflammation in allergic rhinitis

BACKGROUND: The CC-chemokine receptor-3 (CCR3) has emerged as a target molecule for pharmacological intervention in allergic inflammation. OBJECTIVE: To examine whether a dual CCR3 and H(1)-receptor antagonist (AZD3778) affects allergic inflammation and symptoms in allergic rhinitis. METHODS: Patien...

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Autori principali: Greiff, Lennart, Ahlström-Emanuelsson, Cecilia, Bahl, Ash, Bengtsson, Thomas, Dahlström, Kerstin, Erjefält, Jonas, Widegren, Henrik, Andersson, Morgan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833142/
https://ncbi.nlm.nih.gov/pubmed/20144207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-17
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