Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-induced responses in patients with mild asthma: a double-blind, randomised, parallel-group study

BACKGROUND: Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection during childhood may polarise the immune system towards allergen-reactive Th2-type responses in genetically susceptible individuals. T...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Leaker, Brian R., Singh, Dave, Lindgren, Sam, Almqvist, Gun, Eriksson, Leif, Young, Barbara, O’Connor, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924002/
https://ncbi.nlm.nih.gov/pubmed/31856838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1252-2
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