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LINE-1 Retroelements Complexed and Inhibited by Activation Induced Cytidine Deaminase
LINE-1 (abbreviated L1) is a major class of retroelements in humans and mice. If unrestricted, retroelements accumulate in the cytoplasm and insert their DNA into the host genome, with the potential to cause autoimmune disease and cancer. Retroviruses and other retroelements are inhibited by protein...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3487726/ https://ncbi.nlm.nih.gov/pubmed/23133680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049358 |
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