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Intra-Accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats

In order to examine the effect of CART (Cocaine and Amphetamine Regulated Transcript) peptide depletion in adult rats, CART shRNAs or scrambled control shRNAs were administered bilaterally into the nucleus accumbens (NAc). There was an increase in body weight of the shRNA injected rats compared to t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Job, MO, Licata, J, Hubert, GW, Kuhar, MJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487597/
https://ncbi.nlm.nih.gov/pubmed/22975438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.09.005
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