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Intra-Accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats

In order to examine the effect of CART (Cocaine and Amphetamine Regulated Transcript) peptide depletion in adult rats, CART shRNAs or scrambled control shRNAs were administered bilaterally into the nucleus accumbens (NAc). There was an increase in body weight of the shRNA injected rats compared to t...

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Bibliografiske detaljer
Main Authors: Job, MO, Licata, J, Hubert, GW, Kuhar, MJ
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487597/
https://ncbi.nlm.nih.gov/pubmed/22975438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.09.005
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