Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: a phase II study

BACKGROUND: We report a prospective multicenter phase II study of haploidentical hematopoietic stem cell transplantation using CD3/CD19-depleted grafts after reduced intensity conditioning with fludarabine, thiotepa, melphalan and OKT-3. DESIGN AND METHODS: Sixty-one adults with a median age of 46 y...

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Hlavní autoři: Federmann, Birgit, Bornhauser, Martin, Meisner, Christoph, Kordelas, Lambros, Beelen, Dietrich W., Stuhler, Gernot, Stelljes, Matthias, Schwerdtfeger, Rainer, Christopeit, Maximilian, Behre, Gerhard, Faul, Christoph, Vogel, Wichard, Schumm, Michael, Handgretinger, Rupert, Kanz, Lothar, Bethge, Wolfgang A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2012
Témata:
Original Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487553/
https://ncbi.nlm.nih.gov/pubmed/22491731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.059378
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