Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children

BACKGROUND: Natural killer cells have been demonstrated to exert remarkable graft-versus-leukemia effects after haploidentical transplantation. Acquisition of both, inhibiting and activating, receptors on developing natural killer cells is an important step in their functional maturation. Here, we r...

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Detalhes bibliográficos
Main Authors: Pfeiffer, Matthias M., Feuchtinger, Tobias, Teltschik, Heiko-Manuel, Schumm, Michael, Müller, Ingo, Handgretinger, Rupert, Lang, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913088/
https://ncbi.nlm.nih.gov/pubmed/20145268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.021121
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