Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous and aggressive tumor originating from the epithelial lining of the upper aero-digestive tract accounting for 300,000 annual deaths worldwide due to failure of current therapies. The natural killer group 2D (NKG2D) receptors on n...

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Udgivet i:Front Immunol
Main Authors: Weil, Sandra, Memmer, Stefanie, Lechner, Axel, Huppert, Volker, Giannattasio, Ariane, Becker, Tamara, Müller-Runte, Andreas, Lampe, Karen, Beutner, Dirk, Quaas, Alexander, Schubert, Ralf, Herrmann, Eva, Steinle, Alexander, Koehl, Ulrike, Walter, Lutz, von Bergwelt-Baildon, Michael S., Koch, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385630/
https://ncbi.nlm.nih.gov/pubmed/28443091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00387
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