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Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol
Heme-oxygenase 1 is an endoplasmic reticulum-anchored enzyme that breaks down heme into iron, carbon monoxide and biliverdin. Heme is a hydrophobic co-factor in many proteins, including hemoglobin. Free heme is highly cytotoxic and, therefore, both heme synthesis and breakdown are tightly regulated....
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ferrata Storti Foundation
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3487549/ https://ncbi.nlm.nih.gov/pubmed/22419571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.063651 |
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