Heme Oxygenase-1 Reduces Sepsis-Induced Endoplasmic Reticulum Stress and Acute Lung Injury

BACKGROUND: Sepsis leads to severe acute lung injury/acute respiratory distress syndrome (ALI/ARDS) that is associated with enhanced endoplasmic reticulum (ER) stress. Heme oxygenase-1 (HO-1), an ER-anchored protein, exerts antioxidant and protective functions under ALI. However, the role of HO-1 ac...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Chen, Xiaozhen, Wang, Yinglin, Xie, Xiang, Chen, Hongfei, Zhu, Qiqi, Ge, Zhidong, Wei, Hua, Deng, Jingshong, Xia, Zhengyuan, Lian, Qingquan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022325/
https://ncbi.nlm.nih.gov/pubmed/30013453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9413876
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