Tafazzin Knockdown in Mice Leads to a Developmental Cardiomyopathy With Early Diastolic Dysfunction Preceding Myocardial Noncompaction

BACKGROUND: Barth syndrome is a rare, multisystem disorder caused by mutations in tafazzin that lead to cardiolipin deficiency and mitochondrial abnormalities. Patients most commonly develop an early-onset cardiomyopathy in infancy or fetal life. METHODS AND RESULTS: Knockdown of tafazzin (TAZKD) in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Phoon, Colin K. L., Acehan, Devrim, Schlame, Michael, Stokes, David L., Edelman-Novemsky, Irit, Yu, Dawen, Xu, Yang, Viswanathan, Nitya, Ren, Mindong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 2012
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487377/
https://ncbi.nlm.nih.gov/pubmed/23130124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.111.000455
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia