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Unraveling Multiple MHC Gene Associations with Systemic Lupus Erythematosus: Model Choice Indicates a Role for HLA Alleles and Non-HLA Genes in Europeans

We have performed a meta-analysis of the major-histocompatibility-complex (MHC) region in systemic lupus erythematosus (SLE) to determine the association with both SNPs and classical human-leukocyte-antigen (HLA) alleles. More specifically, we combined results from six studies and well-known out-of-...

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Detalhes bibliográficos
Main Authors: Morris, David L., Taylor, Kimberly E., Fernando, Michelle M.A., Nititham, Joanne, Alarcón-Riquelme, Marta E., Barcellos, Lisa F., Behrens, Timothy W., Cotsapas, Chris, Gaffney, Patrick M., Graham, Robert R., Pons-Estel, Bernardo A., Gregersen, Peter K., Harley, John B., Hauser, Stephen L., Hom, Geoffrey, Langefeld, Carl D., Noble, Janelle A., Rioux, John D., Seldin, Michael F., Criswell, Lindsey A., Vyse, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487133/
https://ncbi.nlm.nih.gov/pubmed/23084292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.08.026
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