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Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced and inflammatory liver diseases

MicroRNAs are fine tuners of diverse biological responses and are expressed in various cell types of the liver. Here we hypothesized that circulating microRNAs (miRNAs) may serve as biomarkers of liver damage and inflammation. We studied miRNA-122 that is abundant in hepatocytes and miR-155, -146a a...

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Bibliografiske detaljer
Main Authors: Bala, Shashi, Petrasek, Jan, Mundkur, Shiv, Catalano, Donna, Levin, Ivan, Ward, Jeanine, Alao, Hawau, Kodys, Karen, Szabo, Gyongyi
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486954/
https://ncbi.nlm.nih.gov/pubmed/22684891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25873
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