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Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced and inflammatory liver diseases

MicroRNAs are fine tuners of diverse biological responses and are expressed in various cell types of the liver. Here we hypothesized that circulating microRNAs (miRNAs) may serve as biomarkers of liver damage and inflammation. We studied miRNA-122 that is abundant in hepatocytes and miR-155, -146a a...

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Detalhes bibliográficos
Main Authors: Bala, Shashi, Petrasek, Jan, Mundkur, Shiv, Catalano, Donna, Levin, Ivan, Ward, Jeanine, Alao, Hawau, Kodys, Karen, Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486954/
https://ncbi.nlm.nih.gov/pubmed/22684891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25873
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