Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073

V-073, a small-molecule capsid inhibitor originally developed for nonpolio enterovirus indications is considerably more potent against polioviruses. All poliovirus isolates tested to date (n = 45), including wild, vaccine, vaccine-derived, and laboratory strains, are susceptible to the antiviral cap...

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Autori principali: Liu, Hong-Mei, Roberts, Jason A., Moore, Deborah, Anderson, Barbara, Pallansch, Mark A., Pevear, Daniel C., Collett, Marc S., Oberste, M. Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486616/
https://ncbi.nlm.nih.gov/pubmed/22890765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00539-12
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