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Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073
V-073, a small-molecule capsid inhibitor originally developed for nonpolio enterovirus indications is considerably more potent against polioviruses. All poliovirus isolates tested to date (n = 45), including wild, vaccine, vaccine-derived, and laboratory strains, are susceptible to the antiviral cap...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486616/ https://ncbi.nlm.nih.gov/pubmed/22890765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00539-12 |
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