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In Vitro Antiviral Activity of V-073 against Polioviruses
V-073, an enterovirus capsid inhibitor, was evaluated for its spectrum of antipoliovirus activity. V-073 inhibited all 45 polioviruses tested in a virus-induced cytopathic effect protection assay, with 50% effective concentration (EC(50)) values ranging from 0.003 to 0.126 μM. Ninety percent of the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764203/ https://ncbi.nlm.nih.gov/pubmed/19635956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00671-09 |
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