A Focused Small-Molecule Screen Identifies 14 Compounds with Distinct Effects on Toxoplasma gondii

Toxoplasma gondii is a globally ubiquitous pathogen that can cause severe disease in immunocompromised humans and the developing fetus. Given the proven role of Toxoplasma-secreted kinases in the interaction of Toxoplasma with its host cell, identification of novel kinase inhibitors could precipitat...

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Main Authors: Kamau, Edwin T., Srinivasan, Ananth R., Brown, Mark J., Fair, Matthew G., Caraher, Erin J., Boyle, Jon P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486605/
https://ncbi.nlm.nih.gov/pubmed/22908155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00868-12
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