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Two 2-Hydroxy-3-Alkyl-1,4-Naphthoquinones with In Vitro and In Vivo Activities against Toxoplasma gondii

Two 3-alkyl-substituted 2-hydroxy-1,4-naphthoquinones, NSC 113452 (NSC52) and NSC 113455 (NSC55), were evaluated for activity against Toxoplasma gondii in vitro and in murine models of acute toxoplasmosis. In vitro, both NSC52 and NSC55 significantly inhibited intracellular replication of T. gondii....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Khan, Anis A., Nasr, Mohamed, Araujo, Fausto G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736550/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2284
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