Two 2-Hydroxy-3-Alkyl-1,4-Naphthoquinones with In Vitro and In Vivo Activities against Toxoplasma gondii

Two 3-alkyl-substituted 2-hydroxy-1,4-naphthoquinones, NSC 113452 (NSC52) and NSC 113455 (NSC55), were evaluated for activity against Toxoplasma gondii in vitro and in murine models of acute toxoplasmosis. In vitro, both NSC52 and NSC55 significantly inhibited intracellular replication of T. gondii....

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Antimicrob Agents Chemother
Prif Awduron:	Khan, Anis A., Nasr, Mohamed, Araujo, Fausto G.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1998
Pynciau:	Experimental Therapeutics
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736550/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2284
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