Two 2-Hydroxy-3-Alkyl-1,4-Naphthoquinones with In Vitro and In Vivo Activities against Toxoplasma gondii

Two 3-alkyl-substituted 2-hydroxy-1,4-naphthoquinones, NSC 113452 (NSC52) and NSC 113455 (NSC55), were evaluated for activity against Toxoplasma gondii in vitro and in murine models of acute toxoplasmosis. In vitro, both NSC52 and NSC55 significantly inhibited intracellular replication of T. gondii....

Volledige beschrijving

Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Khan, Anis A., Nasr, Mohamed, Araujo, Fausto G.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1998
Onderwerpen:	Experimental Therapeutics
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736550/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2284
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!