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Introduction of a viral thymidine kinase gene and the human β-globin gene into developmentally multipotential mouse teratocarcinoma cells

Teratocarcinoma (TCC) stem cells provide unique prospects for the introduction of specific genes into mice, by virtue of their dual capacity for propagation in vitro and for normal differentiation in embryos. In this study, we have demonstrated that foreign genes amenable to selection in culture can...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pellicer, Angel, Wagner, Erwin F., Kareh, Adele El, Dewey, Michael J., Reuser, Arnold J., Silverstein, Saul, Axel, Richard, Mintz, Beatrice
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Biological Sciences: Cell Biology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348659/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2098
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