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Introduction of a viral thymidine kinase gene and the human β-globin gene into developmentally multipotential mouse teratocarcinoma cells

Teratocarcinoma (TCC) stem cells provide unique prospects for the introduction of specific genes into mice, by virtue of their dual capacity for propagation in vitro and for normal differentiation in embryos. In this study, we have demonstrated that foreign genes amenable to selection in culture can...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Pellicer, Angel, Wagner, Erwin F., Kareh, Adele El, Dewey, Michael J., Reuser, Arnold J., Silverstein, Saul, Axel, Richard, Mintz, Beatrice
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1980
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348659/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6246522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.4.2098
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