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Antibiotic Resistance and Substrate Profiles of the Class A Carbapenemase KPC-6
The class A carbapenemase KPC-6 produces resistance to a broad range of β-lactam antibiotics. This enzyme hydrolyzes penicillins, the monobactam aztreonam, and carbapenems with similar catalytic efficiencies, ranging from 10(5) to 10(6) M(−1) s(−1). The catalytic efficiencies of KPC-6 against cephem...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486543/ https://ncbi.nlm.nih.gov/pubmed/22908150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01338-12 |
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