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Comparative Pharmacodynamics of the New Oxazolidinone Tedizolid Phosphate and Linezolid in a Neutropenic Murine Staphylococcus aureus Pneumonia Model
Tedizolid phosphate (TR-701) is a novel oxazolidinone prodrug (converted to the active form tedizolid [TR-700]) with potent Staphylococcus aureus activity. The current studies characterized and compared the in vivo pharmacokinetic/pharmacodynamic (PD) characteristics of TR-701/TR-700 and linezolid a...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology
2012
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486526/ https://ncbi.nlm.nih.gov/pubmed/22964254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01303-12 |
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