Comparative Pharmacodynamics of the New Oxazolidinone Tedizolid Phosphate and Linezolid in a Neutropenic Murine Staphylococcus aureus Pneumonia Model

Tedizolid phosphate (TR-701) is a novel oxazolidinone prodrug (converted to the active form tedizolid [TR-700]) with potent Staphylococcus aureus activity. The current studies characterized and compared the in vivo pharmacokinetic/pharmacodynamic (PD) characteristics of TR-701/TR-700 and linezolid a...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Lepak, Alexander J., Marchillo, Karen, Pichereau, Solen, Craig, William A., Andes, David R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486526/
https://ncbi.nlm.nih.gov/pubmed/22964254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01303-12
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items