Comparative Pharmacodynamics of the New Oxazolidinone Tedizolid Phosphate and Linezolid in a Neutropenic Murine Staphylococcus aureus Pneumonia Model

Tedizolid phosphate (TR-701) is a novel oxazolidinone prodrug (converted to the active form tedizolid [TR-700]) with potent Staphylococcus aureus activity. The current studies characterized and compared the in vivo pharmacokinetic/pharmacodynamic (PD) characteristics of TR-701/TR-700 and linezolid a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lepak, Alexander J., Marchillo, Karen, Pichereau, Solen, Craig, William A., Andes, David R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486526/
https://ncbi.nlm.nih.gov/pubmed/22964254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01303-12
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