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N-Glycans on the Nipah Virus Attachment Glycoprotein Modulate Fusion and Viral Entry as They Protect against Antibody Neutralization

Nipah virus (NiV) is the deadliest known paramyxovirus. Membrane fusion is essential for NiV entry into host cells and for the virus' pathological induction of cell-cell fusion (syncytia). The mechanism by which the attachment glycoprotein (G), upon binding to the cell receptors ephrinB2 or eph...

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Библиографические подробности
Главные авторы: Biering, Scott B., Huang, Andrew, Vu, Andy T., Robinson, Lindsey R., Bradel-Tretheway, Birgit, Choi, Eric, Lee, Benhur, Aguilar, Hector C.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486489/
https://ncbi.nlm.nih.gov/pubmed/22915812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01304-12
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