N-Glycans on the Nipah Virus Attachment Glycoprotein Modulate Fusion and Viral Entry as They Protect against Antibody Neutralization

Nipah virus (NiV) is the deadliest known paramyxovirus. Membrane fusion is essential for NiV entry into host cells and for the virus' pathological induction of cell-cell fusion (syncytia). The mechanism by which the attachment glycoprotein (G), upon binding to the cell receptors ephrinB2 or eph...

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Detalles Bibliográficos
Main Authors: Biering, Scott B., Huang, Andrew, Vu, Andy T., Robinson, Lindsey R., Bradel-Tretheway, Birgit, Choi, Eric, Lee, Benhur, Aguilar, Hector C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486489/
https://ncbi.nlm.nih.gov/pubmed/22915812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01304-12
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