Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with α-Ketoisocaproate and l-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis

Branched-chain aminotransferases (BCAT), which utilize pyridoxal 5′-phosphate (PLP) as a cofactor, reversibly catalyze the transfer of the α-amino groups of three of the most hydrophobic branched-chain amino acids (BCAA), leucine, isoleucine, and valine, to α-ketoglutarate to form the respective bra...

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Main Authors: Chen, Chung-De, Lin, Chih-Hao, Chuankhayan, Phimonphan, Huang, Yen-Chieh, Hsieh, Yin-Cheng, Huang, Tien-Feng, Guan, Hong-Hsiang, Liu, Ming-Yih, Chang, Wen-Chang, Chen, Chun-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486342/
https://ncbi.nlm.nih.gov/pubmed/22984263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01659-12
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