Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses

Phylogenetic analysis has demonstrated that some positive-sense RNA viruses can be classified into the picornavirus-like supercluster, which includes picornaviruses, caliciviruses, and coronaviruses. These viruses possess 3C or 3C-like proteases (3Cpro or 3CLpro, respectively), which contain a typic...

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Main Authors: Kim, Yunjeong, Lovell, Scott, Tiew, Kok-Chuan, Mandadapu, Sivakoteswara Rao, Alliston, Kevin R., Battaile, Kevin P., Groutas, William C., Chang, Kyeong-Ok
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2012
נושאים:
Vaccines and Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486288/
https://ncbi.nlm.nih.gov/pubmed/22915796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01348-12
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