Llwytho...

Methotrexate-induced misincorporation of uracil into DNA

A line of human lymphoid cells was tested for the presence of dUMP in DNA with or without treatment with the dihydrofolate reductase inhibitor, methotrexate. Cells treated with methotrexate and labeled with [(3)H]dUrd contained dUMP in DNA in readily detectable amounts (≈0.8 pmol of dUMP per μmol of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Goulian, M., Bleile, B., Tseng, B. Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1980
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC348628/
https://ncbi.nlm.nih.gov/pubmed/6929529
Tagiau: Ychwanegu Tag
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