Uracil misincorporation into DNA and folic acid supplementation(1)(2)(3)

Background: Folate deficiency decreases thymidylate synthesis from deoxyuridylate, which results in an imbalance of deoxyribonucleotide that may lead to excessive uracil misincorporation (UrMis) into DNA during replication and repair. Objective: We evaluated the relation between UrMis in different t...

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Detalhes bibliográficos
Main Authors: Hazra, Aditi, Selhub, Jacob, Chao, Wei-Hsun, Ueland, Per Magne, Hunter, David J, Baron, John A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2010
Assuntos:
Nutritional epidemiology and public health
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793107/
https://ncbi.nlm.nih.gov/pubmed/19923375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.2009.28527
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