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P2X7 receptor activation mediates organic cation uptake into human myeloid leukaemic KG-1 cells

The P2X7 purinergic receptor is an ATP-gated cation channel with an emerging role in neoplasia. In this study we demonstrate that the human KG-1 cell line, a model of acute myelogenous leukaemia, expresses functional P2X7. RT-PCR and immunochemical techniques demonstrated the presence of P2X7 mRNA a...

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Main Authors: Gadeock, Safina, Pupovac, Aleta, Sluyter, Vanessa, Spildrejorde, Mari, Sluyter, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486171/
https://ncbi.nlm.nih.gov/pubmed/22661222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-012-9320-9
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