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The Prolyl Isomerase Pin1 Targets Stem-Loop Binding Protein (SLBP) To Dissociate the SLBP-Histone mRNA Complex Linking Histone mRNA Decay with SLBP Ubiquitination

Histone mRNAs are rapidly degraded at the end of S phase, and a 26-nucleotide stem-loop in the 3′ untranslated region is a key determinant of histone mRNA stability. This sequence is the binding site for stem-loop binding protein (SLBP), which helps to recruit components of the RNA degradation machi...

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Detalhes bibliográficos
Main Authors: Krishnan, Nithya, Lam, TuKiet T., Fritz, Andrew, Rempinski, Donald, O'Loughlin, Kieran, Minderman, Hans, Berezney, Ronald, Marzluff, William F., Thapar, Roopa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486140/
https://ncbi.nlm.nih.gov/pubmed/22907757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00382-12
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