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Knockdown of SLBP results in nuclear retention of histone mRNA

Histone mRNAs are the only eukaryotic cellular mRNAs that are not polyadenylated. Synthesis of mature histone mRNA requires only a single processing reaction: an endonucleolytic cleavage between a conserved stem–loop and a purine-rich downstream element to form the 3′ end. The stem–loop binding prot...

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Detalhes bibliográficos
Main Authors: Sullivan, Kelly D., Mullen, Thomas E., Marzluff, William F., Wagner, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657014/
https://ncbi.nlm.nih.gov/pubmed/19155325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1205409
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