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The Prolyl Isomerase Pin1 Regulates mRNA Levels of Genes with Short Half-Lives by Targeting Specific RNA Binding Proteins

The peptidyl-prolyl isomerase Pin1 is over-expressed in several cancer tissues is a potential prognostic marker in prostate cancer, and Pin1 ablation can suppress tumorigenesis in breast and prostate cancers. Pin1 can co-operate with activated ErbB2 or Ras to enhance tumorigenesis. It does so by reg...

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Detalhes bibliográficos
Main Authors: Krishnan, Nithya, Titus, Mark A., Thapar, Roopa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887067/
https://ncbi.nlm.nih.gov/pubmed/24416409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085427
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