Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro

2-Chlorohexadecanal (2-ClHDA), a chlorinated fatty aldehyde, is formed via attack on ether-phospholipids by hypochlorous acid (HOCl) that is generated by the myeloperoxidase–hydrogen peroxide–chloride system of activated leukocytes. 2-ClHDA levels are elevated in atherosclerotic lesions, myocardial...

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Autors principals: Üllen, Andreas, Fauler, Günter, Bernhart, Eva, Nusshold, Christoph, Reicher, Helga, Leis, Hans-Jörg, Malle, Ernst, Sattler, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2012
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Original Contributions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485557/
https://ncbi.nlm.nih.gov/pubmed/22982051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.08.575
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