Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin

Hypochlorous acid added as reagent or generated by the myeloperoxidase (MPO)-H(2)O(2)-Cl(−) system oxidatively modifies brain ether-phospholipids (plasmalogens). This reaction generates a sn2-acyl-lysophospholipid and chlorinated fatty aldehydes. 2-Chlorohexadecanal (2-ClHDA), a prototypic member of...

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Publicado en:Biochem Pharmacol
Autores principales: Üllen, Andreas, Nusshold, Christoph, Glasnov, Toma, Saf, Robert, Cantillo, David, Eibinger, Gerald, Reicher, Helga, Fauler, Günter, Bernhart, Eva, Hallstrom, Seth, Kogelnik, Nora, Zangger, Klaus, Oliver Kappe, C., Malle, Ernst, Sattler, Wolfgang
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Science 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321883/
https://ncbi.nlm.nih.gov/pubmed/25576489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.12.017
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