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Intravenous Delivery of Targeted Liposomes to Amyloid-β Pathology in APP/PSEN1 Transgenic Mice

Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer’s disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents that...

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Main Authors: Tanifum, Eric A., Dasgupta, Indrani, Srivastava, Mayank, Bhavane, Rohan C., Sun, Li, Berridge, John, Pourgarzham, Hoda, Kamath, Rashmi, Espinosa, Gabriela, Cook, Stephen C., Eriksen, Jason L., Annapragada, Ananth
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485335/
https://ncbi.nlm.nih.gov/pubmed/23119043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048515
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