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Glucose-sensing pulmonary delivery of human insulin to the systemic circulation of rats

In an attempt to achieve post-inhalation self-regulated insulin release, we constructed a microparticle agglomerate of nano-sized liposomal particles, with the agglomeration facilitated by cross-linkages capable of cleavage by glucose. The particles exhibited a small aerodynamic diameter within the...

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Autori principali: Karathanasis, Efstathios, Bhavane, Rohan, Annapragada, Ananth V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676664/
https://ncbi.nlm.nih.gov/pubmed/18019848
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